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Descriptor English: Ganglionic Blockers
Descriptor Spanish: Bloqueadores Ganglionares
Descriptor bloqueantes ganglionares
Entry term(s) fármacos bloqueantes ganglionares
fármacos ganglioplégicos
ganglioplégicos
Scope note: Sustancias cuya acción principal es la interrupción de la transmisión neural en los receptores nicotínicos de las neuronas posganglionares del sistema nervioso autónomo. Debido a la diversidad de sus acciones, entre las que se encuentra el bloqueo de los sistemas simpático y parasimpático, su uso terapéutico ha sido sustituido en gran medida por fármacos más específicos. Aún pueden utilizarse para controlar la tensión sanguínea en pacientes con aneurisma disecante agudo de la aorta y para inducir hipotensión en intervenciones quirúrgicas.
Descriptor Portuguese: Bloqueadores Ganglionares
Descriptor French: Ganglioplégiques
Entry term(s): Agents, Ganglionic Blocking
Agents, Ganglioplegic
Blockaders, Ganglionic
Blockers, Ganglionic
Blocking Agents, Ganglionic
Ganglionic Blockaders
Ganglionic Blocking Agents
Ganglioplegic Agents
Tree number(s): D27.505.696.663.050.340
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005730
Scope note: Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 95; was GANGLIONIC BLOCKADERS 1970-94; was GANGLIONIC-BLOCKING AGENTS 1963-69
Online Note: use GANGLIONIC BLOCKERS to search GANGLIONIC BLOCKADERS 1970-94 & GANGLIONIC-BLOCKING AGENTS 1966-69
History Note: 95; was GANGLIONIC BLOCKADERS 1970-94; was GANGLIONIC-BLOCKING AGENTS 1963-69
Entry Version: GANGLIONIC BLOCK
Related: Nicotinic Antagonists MeSH
Receptors, Nicotinic MeSH
DeCS ID: 5871
Unique ID: D005730
NLM Classification: QV 132
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1970/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
Ganglionic Blockers - Preferred
Concept UI M0008985
Scope note Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Preferred term Ganglionic Blockers
Entry term(s) Agents, Ganglionic Blocking
Agents, Ganglioplegic
Blockaders, Ganglionic
Blockers, Ganglionic
Blocking Agents, Ganglionic
Ganglionic Blockaders
Ganglionic Blocking Agents
Ganglioplegic Agents



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